Best initial DMARD in RA,”Methotrexate SE = GI upset, oral ulcers, mild alopecia, bone marrow suppression (also give folinic acid), hepatocellular injury, interstitial pneumonitis Closely monitor liver and renal function Alternative = leflunomide or hydroxychloroquine, sulfasalazine

Best initial DMARD in RA,”Methotrexate SE = GI upset, oral ulcers, mild alopecia, bone marrow suppression (also give folinic acid), hepatocellular injury, interstitial pneumonitis Closely monitor liver and renal function Alternative = leflunomide or hydroxychloroquine, sulfasalazine

Anti-TNF inhibiting agents”