General characteristics of paroxysmal nocturnal hemoglobinuria,”Acquired – affects cells of all blood lineages Deficiency of anchor proteins (CD55, CD59) that link complement inactivating proteins to blood cell membranes. Results in susceptibility to complement-mediated lysis of RBCs

General characteristics of paroxysmal nocturnal hemoglobinuria,”Acquired – affects cells of all blood lineages Deficiency of anchor proteins (CD55, CD59) that link complement inactivating proteins to blood cell membranes. Results in susceptibility to complement-mediated lysis of RBCs

WBCs and platelets”