Abnormal hemostasis in patients with chronic renal failure?,”Platelet dysfunction is the most common cause of abnormal hemostasis in patients with CRF. PT, PTT, and platelet counts are normal. BT is prolonged. DDAVP is usually the treatment of choice
if needed. DDAVP increases the release of factor VIII: von Willebrand factor multimers from endothelial storage sites. Platelet transfusion is not indicated because the transfused platelets quickly become inactive.”