Malignant biliary obstruction?,”Clinical presentations that may suggest malignant biliary obstruction are painless jaundice, pruritus, weight loss, with PE being normal or showing RUQ tenderness, mass, hepatomegaly. Labs show increased direct bilirubin, increased alkaline phosphatase, and normal to increased AST & ALT. Common causes are pancreatic or biliary cancer, gallstones
and benign biliary strictures.”