Ras^D,”mutant oncogene lacks GTPase activity, associated w/ numerous cancersconstitutively activeis a dominate active (aka dominant gain-of-function) alleleloses GTPase activity by altering any 1 of G12, G13, A59, G13, Q61
K117 or A146 to X”
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Ras^D,”mutant oncogene lacks GTPase activity, associated w/ numerous cancersconstitutively activeis a dominate active (aka dominant gain-of-function) alleleloses GTPase activity by altering any 1 of G12, G13, A59, G13, Q61
K117 or A146 to X”