Beta-thalassemia?

Beta-thalassemia?

Beta-thalassemia comes in two severities. Beta-thalassemia minor results from a defect in 1 beta-thalassemia gene. It manifests as a modest anemia with hematocrits between 28-40%. The MCV typically ranges between 55-75 fl. Beta-thalassemia major occurs when both beta-thalassemia genes are defective. It is characterized by severe anemia and transfusion dependence at an early age. Beta-thalassemia is most likely seen on those with European descent.