Cushing’s syndrome?,”Cushing’s syndrome is caused by corticosteroid excess (eg, asthmatic who takes multiple steroid medication). The signs and symptoms of Cushing’s syndrome include fatigue, weight gain, easy bruising, central adiposity, proximal muscle weakness, hyperglycemia, osteopenia and osteoporosis, hypertension, acne, cataracts, and susceptibility to infections. Hypokalemia and hypernatremia are the electrolyte abnormalities most commonly observed due to increased aldosterone production. If severe

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Central retinal artery occlusion secondary to embolism?,”PlPainless loss of monocular vision is the usual presenting symptom. Embolism of the retinal artery is the most common cause of ocular stroke. CRAO is an ophthalmologic emergency. A delay in treatment may result in permanent loss of vision. Immediate intervention includes ocular massage

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Heparin-induced thrombocytopenia?,”Suspected heparin-induced thrombocytopenia requires immediate cessation of all forms of heparin, laboratory testing to confirm diagnosis (serotonin release assay), and starting alternative anticoagulants (eg, direct thrombin inhibitors) even if thrombosis has not occurred. Warfarin is usually started after treatment with a non-heparin anticoagulant and platelet count recovery to > 150

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Chronic liver disease?,”Chronic liver disease with resultant cirrhosis can cause hypogonadism. Cirrhosis due to alcohol or hemochromatosis can be associated with hypogonadism, likely due to primary gonadal injury or H-P dysfunction. Findings in men with cirrhosis include telangiectasias, palmar erythema, testicular atrophy, gynecomastia

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“Osteoarthritis, aka degenerative joint disease?”,”Degenerative joint disease presents in adults over age 40 with indolent progressive anterior hip pain worsened by activity and relieved by rest. Morning stiffness or stiffness after prolonged resting is a consistent feature, but in contrasts to rheumatoid arthritis, the morning stiffness of osteoarthritis lasts less than 30 to 60 minutes. The hip is not tender to palpation, but may be limited to active and passive internal and external rotation

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