What is the approach to hemoptysis?,”Airway – epistaxis, upper GI bleed (Dieulafoy), neoplasm, foreign body, fistulasParenchymal:1. Infection2. Rheumatic (GBM, SLE, GPA, Behcets, idiopathic pulmonary hemosiderosis)3. Connective tissue (Ehlers-Danlos)4. Coagulopathy (thrombocytopenia, drugs)Miscellanous (catamenial, cocaine, nitrogen oxide)Vascular – PE, AVM, pulmonary HTN, CHF

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What is the approach to conjugated hyperbilirubinemia??,”Conjugated (always hepatic):Hepatocellular damage – Viral hepatitis, alcohol, drugs (acetaminophen, INH, statins), sepsis/infectionsIntrahepatic cholestasis – Infiltrates (CA, infection, sarcoid), drugs (OCP, Beta-lactams), reduced excretion (Dubin Johnson, Rotor’s)Biliary obstruction – stones, bile duct carcinoma, PSC

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