How do you workup hypernatremia (Na > 145)Treatment?,”First measure ECFLow = Hypovolemic hypernatremia (↓↓H2O, ↓Na). Due to renal loss (diuretic) or extrarenal loss (diarrhea). Treat with isotonic salineNormal = Isovolemic hypernatremia (↓H2o, -Na). Due to DI. Treat with D5W or 0.45 salineHigh = Hypervolemic hypernatremia (↑H2O, ↑↑Na). Due to cushings, primary aldosteronism
steroids. Treat with diuretics + D5W DN exceed 8 for the first 24hrs (cerebral edema)”