HW: (Fret Graphs)You observe the following activity profiles upon the addition and subsequent removal of EGF to a mutant cell line. RTK activity of HER1=1; MEK activity=1; MAPK activity=4. Which of the following could explain this result?

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HW: (Fret Graphs)You observe the following activity profiles upon the addition and subsequent removal of EGF to a mutant cell line. RTK activity of HER1=1; MEK activity=1; MAPK activity=4. Which of the following could explain this result?

T183 on MAPK is changed to A and Y185 on MAPK is changed to F

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