Toxic epidermal necrolysis (TEN)?,”TEN is a severe syndrome characterized by the sudden onset of mucocutaneous lesions and systemic signs of toxicity. Typical features include an erythematous eruption that rapidly evolves into exfoliation of the skin. It is most often caused by medications (eg, antibiotics, anticonvulsants, allopurinol). TEN and Stevens, Johnson syndrome (SJS) are similar disorders distinguished by the percentage of involved skin: SSJ involves < 10% of the body surface area, TEN involves > 30

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Molluscum contagiosum (MC),”MC is a skin infection caused by a poxvirus. It is characterized by small, pruritic, skin-colored papules with umbilicated centers. Children are most commonly affected, but adolescents and adults also can develop MC.Transmission occurs through skin-to-skin contact or via contaminated fomites, with subsequent autoinoculation to additional sites. MC is self-limited (resolution within 6-12 months), but treatment with curettage, cryotherapy, or topical agents (eg, podophyllotoxin) may be considered to prevent further spread, reduce symptoms, or improve cosmesis. HIV testing should be considered for patients with MC, especially if they have large (> 10 mm), numerous

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Malignant biliary obstruction?,”Clinical presentations that may suggest malignant biliary obstruction are painless jaundice, pruritus, weight loss, with PE being normal or showing RUQ tenderness, mass, hepatomegaly. Labs show increased direct bilirubin, increased alkaline phosphatase, and normal to increased AST & ALT. Common causes are pancreatic or biliary cancer, gallstones

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