Parkinsons,”Loss of dopamine results in unopposed AchTRAPS-Tremor (at rest)-Rigidity (cogwheel)-Akinesia (or bradykinesia)-Postural instability-Shuffling gait*May also have small-handwriting, opthommalplegiaOnset usually > 50Dx: Lewy bodiesTreat (increase dopa or reduce ACh)-Carbidopa-levodopa (s/e: tardive dyskinesia after yrs)-Dop agonists (bromocriptine
pramipexole)-Segeline: MOA B inhibitor-Amantadine-Anticholingeric: Benztropine-Amitriptyline-DBS if severe or onset < 40"