Proto-Oncogenes,”the cancer genesnormal genes that have normal proliferation but are going to go rogue and become oncogenespromote cell survival or proliferationex) HER2, Ras, Raf, Abl, Myceffect of mutation: gain-of-function mutations allow unregulated cell proliferation and survivalmutations genetically dominantarise by point mutation, chromosomal translocation
amplification”