Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Cancer Hallmarks 1) sustained proliferative[…]
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Oncogene addiction,”oncogene responsible for allowing cancer cell to adept and proliferate knock it out
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Oncogene addiction,”oncogene responsible for allowing[…]
Read more“HW: Which combination of drugs would most effectively treat a tumor w/ “”sustained proliferative signaling”” & “”replicative immortality”” as its 2 main cancer hallmarks?”
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.“HW: Which combination of drugs[…]
Read moreHW: Which of the following pairs of cancer hallmarks would be most directly eliminated if you could restore p53 function (e.g. with a chaperone therapy) in tumor cells?
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.HW: Which of the following[…]
Read moreVariety of treatments to choose from…,”90% of drugs don’t do anythingvast majority target kinases (ser/thr)problematic: never going to be able to achieve tumor specificity that you wanttypically much more specific
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Variety of treatments to choose[…]
Read moreHW: Which is the largest functional class of protein targets for chemotherapeutic drugs currently in use?
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.HW: Which is the largest[…]
Read moreAngiogenesis,”prevent vascularization by targeting normal epithelial cells?cutting off access to circulatory system; cutting off oxygen, glucose, opportunities for metastasis-all good!but also cutting out means by which drug gets delivered to cancer…cells will actually proliferate more aggressively than they did in the absence of the drugcan make a drug that works too well
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Angiogenesis,”prevent vascularization by targeting normal[…]
Read moreCancer Moonshot
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Cancer Moonshot long list of[…]
Read moreDrivers
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Drivers changes actually being selected[…]
Read morePassengers
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Passengers other mutations that occurred[…]
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