Uncomplicated cystitis?,”In patients with suggestive clinical findings (eg, dysuria, urgency, suprapubic tenderness), urinalysis will confirm diagnosis and patients can be treated without urine culture. Culture is reserved for those who fail initial therapy. Preferred treatment options include trimethoprim-sulfamethoxazole (3 days), nitrofurantoin (5 days), and fosfomycin (single dose). Fluoroquinolones are also effective but are typically reserved for patients who cannot take the above options (eg
sulfa allergy) or for settings with high local resistance rates.”