Warber Effect,”Cancer cells going through glycolysis, convert most carbon to lactate (most lactate gets excreted from the cells)Person intakes a lot of Vitamin C (taking advantage of phenotype Ras driven cancer cells) Glutaphine immediately going to be reduced, but putting a high concentration of itgoing to have pleiotropic affects in cellscell becomes depleted of reduced glutaphine, and also w/ NADPHnow becomes oxidized environmentstart forming disulfide bonds in cytosol that shouldn’t be thereReactive oxygen species come in and damage DNA (severe damage)–>going to shut glycolysis down, has to switch over to mitochondria in oxidative phosphorylation to generate ATP (cell starting to starve itself

Warber Effect,”Cancer cells going through glycolysis, convert most carbon to lactate (most lactate gets excreted from the cells)Person intakes a lot of Vitamin C (taking advantage of phenotype Ras driven cancer cells) Glutaphine immediately going to be reduced, but putting a high concentration of itgoing to have pleiotropic affects in cellscell becomes depleted of reduced glutaphine, and also w/ NADPHnow becomes oxidized environmentstart forming disulfide bonds in cytosol that shouldn’t be thereReactive oxygen species come in and damage DNA (severe damage)–>going to shut glycolysis down, has to switch over to mitochondria in oxidative phosphorylation to generate ATP (cell starting to starve itself

undergo apoptosis)incredibly specific-only for cancer cellstargeting cells expressing higher levels of GLUT1″