What are the causes of ANION gap metabolic acidosis? What is the approach to investigating?,”KARMELKetosis (diabetic, alcoholic, starvation)ASA (salicylates)Renal (AKI, uremia)MethanolEthylene glycolLactic acid (Type B – Metformin, Iron, INH, Valproate
etc)1. Lactate level (rules out 90% of causes)2. Ketone level (3 causes of ketosis)3. Creatinine (renal)4. Then consider rest”