What does the mediastinum contain?,”Heart, Large vessels, Bronchi, Trachea, Esophagus June 24, 2017 mfadmin Surgical Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review. What does the mediastinum contain?,”Heart, Large vessels, Bronchi, Trachea, Esophagus Thymus gland”