What is the approach to conjugated hyperbilirubinemia??,”Conjugated (always hepatic):Hepatocellular damage – Viral hepatitis, alcohol, drugs (acetaminophen, INH, statins), sepsis/infectionsIntrahepatic cholestasis – Infiltrates (CA, infection, sarcoid), drugs (OCP, Beta-lactams), reduced excretion (Dubin Johnson, Rotor’s)Biliary obstruction – stones, bile duct carcinoma, PSC
pancreatitis”