What is the drug for acetaminophen toxicity? How do we determine if to treat and how soon should it be given? Describe single dose vs multiple dose and other criteria.,”N-acetylcysteine (Mucomist) IV or PO.Ideally given within 8 hours to prevent liver damage.Single dose – use Rhumack-Matthew Nomogram Multiple dose
chronic user – treat if liver enzymes elevated or acetaminophen level is presentHx of any dose over 10 g or 150 mg/kg (200 mg/kg in children). Treat without an acetaminophen level.”