Central vs nephrogenic DI,”Central-Idiopathic or pituitary tumor-Urine specific gravity < 1.006-Serum osmolarity > 280-Treat: Desmopressin (DDAVP)Nephrogenic-Li or demeclocycline (both inhibit ADH)-Urine specific gravity < 1.006-Serum osmolarity > 280-Treat: HCTZ

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Central vs nephrogenic DI,”Central-Idiopathic or pituitary tumor-Urine specific gravity < 1.006-Serum osmolarity > 280-Treat: Desmopressin (DDAVP)Nephrogenic-Li or demeclocycline (both inhibit ADH)-Urine specific gravity < 1.006-Serum osmolarity > 280-Treat: HCTZ

indomethacin*Normal plasma osmolarity is 250-290″