Clinical features of B12 deficiency,”Macrocytic anemiaSore tongue (stomatitis and glossitis) Neuropathy! from demyelination of posterior columns, lateral CST and spinocerebellar tracts –> loss of position/vibratory sensation in lower ext, ataxia, upper motor neuron signs (increased DTR, spasticity, weakness

Clinical features of B12 deficiency,”Macrocytic anemiaSore tongue (stomatitis and glossitis) Neuropathy! from demyelination of posterior columns, lateral CST and spinocerebellar tracts –> loss of position/vibratory sensation in lower ext, ataxia, upper motor neuron signs (increased DTR, spasticity, weakness

Babinkski sign)”