What are the etiologies of adverse drug reactions?,”ABCDEType A – Augmented. Dose dependent and predictable from the known pharmacology of the medication (75% of all ADR)Type B – Bizarre. Idiosyncratic or immunologic, unrelated to pharmacology (anaphylaxis, MH, etc). NEVER USE AGAIN.Type C – Chronic. Cumulative dose related (e.g. adrenal insufficiency). Type D – Delayed. Late effects (E.g. teratogenic, carcinogenic, tardive dyskinesia). Type E – End of use. Withdrawal (e.g. opioids). Therefore

What are the etiologies of adverse drug reactions?,”ABCDEType A – Augmented. Dose dependent and predictable from the known pharmacology of the medication (75% of all ADR)Type B – Bizarre. Idiosyncratic or immunologic, unrelated to pharmacology (anaphylaxis, MH, etc). NEVER USE AGAIN.Type C – Chronic. Cumulative dose related (e.g. adrenal insufficiency). Type D – Delayed. Late effects (E.g. teratogenic, carcinogenic, tardive dyskinesia). Type E – End of use. Withdrawal (e.g. opioids). Therefore

withdrawl slowly.”