Defect in hereditary spherocytosis
Autosomal dominant mutation in spectrin (decreased but not totally absent) Loss of membrane surface area but not volume Sperhical RBCs are trapped and destroyed by the spleen
The goto resource for studying materials
Defect in hereditary spherocytosis
Autosomal dominant mutation in spectrin (decreased but not totally absent) Loss of membrane surface area but not volume Sperhical RBCs are trapped and destroyed by the spleen