Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Cold AIHA,”IgM 0-5C Intravascular hemolysis[…]
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Warm AIHA,”More commonIgG binds to RBCs optimally at 37C Extravascular hemolysis – primary site of sequestration is the spleen. Splenomegaly is a common feature. Mostly idiopathic. Can be secondary to lymphomas, leukemias (CLL), other malignancies, collagen vascular disease (SLE)
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Read moreLab test for G6PD def
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Lab test for G6PD def[…]
Read morePeripheral smear of G6PD def
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Read morePrecipitants of G6PD def crisis,”Sulonamides, nitrofurantoin, primaquine, dimercaperol, fava beans
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Precipitants of G6PD def crisis,”Sulonamides,[…]
Read moreMutation in G6PD def,”X-linked recessive so primarly affects men Deficiency leads to accumulation of unneutralized H202 which denatures Hgb, precipitating Heinz body formation that attack to RBC membranes which reduce flexibility, destroyed by spleen A variant: older RBCs are destroyed, young are spared. Usually triggered by infection or by rdugs Severe form: usually in Mediterranean descent
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Read moreDefect in hereditary spherocytosis
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Read moreCauses of spherocytosis
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Causes of spherocytosis HereditaryG6PD def[…]
Read moreWhat organisms are sickle cell patients at risk of getting?,”Because of functional asplenia they are at risk for encapsulated organisms: H flu, strep pnaAlso salmonella osteomyelitis Get early vaccines for strep pna
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Read moreWhat urine trait is sickle cell trait associated with?
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.What urine trait is sickle[…]
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