Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Causes of spherocytosis HereditaryG6PD def[…]
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Defect in hereditary spherocytosis
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Defect in hereditary spherocytosis Autosomal[…]
Read moreMutation in G6PD def,”X-linked recessive so primarly affects men Deficiency leads to accumulation of unneutralized H202 which denatures Hgb, precipitating Heinz body formation that attack to RBC membranes which reduce flexibility, destroyed by spleen A variant: older RBCs are destroyed, young are spared. Usually triggered by infection or by rdugs Severe form: usually in Mediterranean descent
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Mutation in G6PD def,”X-linked recessive[…]
Read morePrecipitants of G6PD def crisis,”Sulonamides, nitrofurantoin, primaquine, dimercaperol, fava beans
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Read morePeripheral smear of G6PD def
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Read moreLab test for G6PD def
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Read moreWarm AIHA,”More commonIgG binds to RBCs optimally at 37C Extravascular hemolysis – primary site of sequestration is the spleen. Splenomegaly is a common feature. Mostly idiopathic. Can be secondary to lymphomas, leukemias (CLL), other malignancies, collagen vascular disease (SLE)
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Warm AIHA,”More commonIgG binds to[…]
Read moreCold AIHA,”IgM 0-5C Intravascular hemolysis Primary site of sequestration is the liver Can be idiopathic (elderly)
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Cold AIHA,”IgM 0-5C Intravascular hemolysis[…]
Read moreDiagnosis of AIHA
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Diagnosis of AIHA Direct Coombs[…]
Read moreTreatment for warm AIHA
Average Rating 0 out of 5 stars. 0 votes.You must log in to submit a review.Treatment for warm AIHA GlucocorticoidsSplenectomy[…]
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